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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2068 | Cyclotraxin B | ||
Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also sho... | |||
TP2068L | Cyclotraxin B acetate(1203586-72-4 free base) | Trk receptor | |
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold... | |||
T75832 | Cyclotraxin B TFA | ||
Cyclotraxin B TFA, a cyclic peptide, serves as a highly potent and selective non-competitive inhibitor of TrkB, effectively impeding BDNF-triggered TrkB activity without altering BDNF binding affinity, evidenced by an IC... |